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Debut fulminant într-un sindrom cerebro-metastic- prezentare de caz. Source: Romanian Journal of Neurology.

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Author s : Hancu, A. Abstract: Introduction. After lungs and breast cancer, melanoma is the third cause that can lead to brain metastasis; this are often more than one and could be hemorrhages.

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We present the case of a 43 years old male, without any known medical history, who suddenly has headaches, mentat confusion and vomiting.

CT and MRl cerebral papillomatosis skin w ith and w ithout contrast reveals cortico-subcortical brain masses in frontal, parietal, temporal and occipital lobes both parts and also in right thalamic region. Displacement of midsaggita!

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Scans conclusions: brain metastasis, some of them with hemorrhagic content. By performing thorax, abdominal and pelvic CT scans we ruled out primary tumors.

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Dermatological exam showed no abnormalities. The evolution of the patient was unfavorable under symptomatic treatment.

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The patient became tetra paretic and restlessness. The patient was transferred to Coientina Hospital Neurology Section where brain biopsy o f the left frontal mass was made.

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The biopsy revealed a typical hystopatological and immunohystochimical aspect of brains metastasis which originated from malign melanoma.

Malign melanomas often can determine brain metastasis before a skin lesion appears.

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The particularity of this case is the acute onset, rarely found in cerebro-metastatic syndrome. English Copyright of Romanian Journal of Neurology is the property of Amaltea Medical Publishing House and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission.

However, users may print, download, or email articles for individual use.

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This abstract may be abridged. No warranty is given about the accuracy of the copy.

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